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BOULMEDAIS Fouzia

Fouzia BOULMEDAIS

CNRS Researcher

E-mail : fouzia.boulmedais_AT_ics-cnrs.unistra.fr

Tel : 03.88.41.41.60

Office : A336

Equipe : Ingénierie Macromoléculaire aux Interfaces

Team : Macromolecular Engineering at Interfaces

Research Interest

  • Buildup and structure of polyelectrolyte multilayer films : influence of an electric potential and cyclic voltamperometry.
  • Self-construction of films by electrochemistry
  • Incorporation of bioactive molecules in multilayer films and their controlled release
  • Development of polymeric matrices for tissue engineering

Professional Experience

Since Jan. 2012 : Deputy director of ICS

Since Jan. 2006 : CNRS researcher at ICS

Fev. 2005 - Dec. 2005 : Post doctoral fellowship at CNRS UMR 6510 (Rennes, France)

Nov. 2003 - Dec. 2004 : Post doctoral fellowship at ETH Zürich (Switzerland) and MPI (Golm, Germany).

Formation

2010 : "Habilitation à diriger des recherches" University of Strasbourg

2003 : Ph.D., Chemistry and Physical Chemistry, University Louis Pasteur (Strasbourg)

2000 : Engineer in Process Engineering, ENSIC (Nancy)

Collaborations

  • INSERM UMR 977 (Strasbourg) - Dr Jean-Claude Voegel
  • CNRS UMR 7175 (Strasbourg) - Dr Benoit Frisch
  • IPCMS (Strasbourg) - Prof. Sylvie Begin, Dr. Benoit Pichon and Dr. Delphine Felder
  • EA 246 (Reims) - Dr Halima Kerdjoudj
  • ETH-Zürich (Switzerland) - Prof. Janos Vörös
  • University of Bayreuth (Germany) - Prof. A. Fery
  • Institute of polymer science and technology CSIC (Madrid, Spain)- Dr. Rebeca Hernandez
  • Polytechnico di turino (Alessandria, Italy) - Dr Federico Carosio

List of publications

2017

Alami, S. M., Rammal, H., Boulagnon-Rombi, C., Velard, F., Lazar, F., Drevet, R., et al. (2017). Harnessing Wharton's jelly stem cell differentiation into bone-like nodule on calcium phosphate substrate without osteoinductive factors. Acta Biomater., 49, 575–589.
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Criado, M., Rebollar, E., Nogales, A., Ezquerra, T. A., Boulmedais, F., Mijangos, C., et al. (2017). Quantitative Nanomechanical Properties of Multilayer Films Made of Polysaccharides through Spray Assisted Layer-by-Layer Assembly. Biomacromolecules, 18(1), 169–177.
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Mutschler, A., Betscha, C., Ball, V., Senger, B., Vrana, N. E., Boulmedais, F., et al. (2017). Nature of the Polyanion Governs the Antimicrobial Properties of Poly(arginine)/Polyanion Multilayer Films. Chemistry of Materials, 29(7), 3195–3201.
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Rammal, H., Dubus, M., Aubert, L., Reffuveille, F., Laurent-Maquin, D., Terryn, C., et al. (2017). Bioinspired Nanofeatured Substrates: Suitable Environment for Bone Regeneration. ACS Appl. Mater. Interfaces, 9(14), 12791–12801.
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Rammal, H., Harmouch, C., Maerten, C., Gaucher, C., Boulmedais, F., Schaaf, P., et al. (2017). Upregulation of endothelial gene markers in Wharton's jelly mesenchymal stem cells cultured on polyelectrolyte multilayers. J. Biomed. Mater. Res. Part A, 105(1), 292–300.
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2016

Lavalle, P., Boulmedais, F., Schaaf, P., & Jierry, L. (2016). Soft-Mechanochemistry: Mechanochemistry Inspired by Nature. Langmuir, 32(29), 7265–7276.
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Zahouani, S., Chaumont, A., Senger, B., Boulmedais, F., Schaaf, P., Jierry, L., et al. (2016). Stretch-Induced Helical Conformations in Poly(L-lysine)/Hyaluronic Acid Multilayers. ACS Appl. Mater. Interfaces, 8(24), 14958–14965.
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2015

Bacharouche, J., Degardin, M., Jierry, L., Carteret, C., Lavalle, P., Hemmerle, J., et al. (2015). Multivalency: influence of the residence time and the retraction rate on rupture forces measured by AFM. Journal of Materials Chemistry B, 3(9), 1801–1812.
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Chaubaroux, C., Perrin-Schmitt, F., Senger, B., Vidal, L., Voegel, J. - C., Schaaf, P., et al. (2015). Cell Alignment Driven by Mechanically Induced Collagen Fiber Alignment in Collagen/Alginate Coatings. Tissue Engineering Part C-Methods, 21(9), 881–888.
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De Leon, A. S., Garnier, T., Jierry, L., Boulmedais, F., Munoz-Bonilla, A., & Rodriguez-Hernandez, J. (2015). Enzymatic Catalysis Combining the Breath Figures and Layer-by-Layer Techniques: Toward the Design of Microreactors. Acs Applied Materials & Interfaces, 7(22), 12210–12219.
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Dochter, A., Garnier, T., Pardieu, E., Nguyet Trang Thanh, C., Maerten, C., Senger, B., et al. (2015). Film Self-Assembly of Oppositely Charged Macromolecules Triggered by Electrochemistry through a Morphogenic Approach. Langmuir, 31(37), 10208–10214.
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Garnier, T., Dochter, A., Chau, N. T. T., Schaaf, P., Jierry, L., & Boulmedais, F. (2015). Surface confined self-assembly of polyampholytes generated from charge-shifting polymers. Chemical Communications, 51(74), 14092–14095.
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Longo, J., Yao, C., Rios, C., Nguyet Trang Thanh, C., Boulmedais, F., Hemmerle, J., et al. (2015). Reversible biomechano-responsive surface based on green fluorescent protein genetically modified with unnatural amino acids. Chemical Communications, 51(1), 232–235.
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Maerten, C., Garnier, T., Lupattelli, P., Nguyet Trang Thanh, C., Schaaf, P., Jierry, L., et al. (2015). Morphogen Electrochemically Triggered Self-Construction of Polymeric Films Based on Mussel-Inspired Chemistry. Langmuir, 31(49), 13385–13393.
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Pardieu, E., Pronkin, S., Dolci, M., Dintzer, T., Pichon, B. P., Begin, D., et al. (2015). Hybrid layer-by-layer composites based on a conducting polyelectrolyte and Fe3O4 nanostructures grafted onto graphene for supercapacitor application. Journal of Materials Chemistry A, 3(45), 22877–22885.
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Rios, C., Longo, J., Zahouani, S., Garnier, T., Vogt, C., Reisch, A., et al. (2015). A new biomimetic route to engineer enzymatically active mechano-responsive materials. Chemical Communications, 51(26), 5622–5625.
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Rydzek, G., Ji, Q., Li, M., Schaaf, P., Hill, J. P., Boulmedais, F., et al. (2015). Electrochemical nanoarchitectonics and layer-by-layer assembly: From basics to future. Nano Today, 10(2), 138–167.
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Rydzek, G., Toulemon, D., Garofalo, A., Leuvrey, C., Dayen, J. - F., Felder-Flesch, D., et al. (2015). Selective Nanotrench Filling by One-Pot Electroclick Self-Constructed Nanoparticle Films. Small, 11(36), 4638–4642.
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Seon, L., Lavalle, P., Schaaf, P., & Boulmedais, F. (2015). Polyelectrolyte Multi layers: A Versatile Tool for Preparing Antimicrobial Coatings. Langmuir, 31(47), 12856–12872.
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Vigier-Carriere, C., Garnier, T., Wagner, D., Lavalle, P., Rabineau, M., Hemmerle, J., et al. (2015). Bioactive Seed Layer for Surface-Confined Self-Assembly of Peptides. Angewandte Chemie-International Edition, 54(35), 10198–10201.
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2014

Carosio, F., Colonna, S., Fina, A., Rydzek, G., Hemmerle, J., Jierry, L., et al. (2014). Efficient Gas and Water Vapor Barrier Properties of Thin Poly(lactic acid) Packaging Films: Functionalization with Moisture Resistant Nafion and Clay Multilayers. Chemistry of Materials, 26(19), 5459–5466.
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Melin, F., Noor, M. R., Pardieu, E., Boulmedais, F., Banhart, F., Cecchini, G., et al. (2014). Investigating the Thermostability of Succinate: Quinone Oxidoreductase Enzymes by Direct Electrochemistry at SWNTs-Modified Electrodes and FTIR Spectroscopy. Chemphyschem, 15(16), 3572–3579.
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Reisch, A., Roger, E., Phoeung, T., Antheaume, C., Orthlieb, C., Boulmedais, F., et al. (2014). On the Benefits of Rubbing Salt in the Cut: Self-Healing of Saloplastic PAA/PAH Compact Polyelectrolyte Complexes. Advanced Materials, 26(16), 2547–2551.
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Seon, L., Parat, A., Gaudiere, F., Voegel, J. - C., Auzely-Velty, R., Lorchat, P., et al. (2014). Influence of the Interaction Strength between Supramolecular Complexes on the Topography of Neutral Polymer Multilayer Films. Langmuir, 30(22), 6479–6488.
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2013

Cado, G., Aslam, R., Seon, L., Garnier, T., Fabre, R., Parat, A., et al. (2013). Self-Defensive Biomaterial Coating Against Bacteria and Yeasts: Polysaccharide Multilayer Film with Embedded Antimicrobial Peptide. Advanced Functional Materials, 23(38), 4801–4809.
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Davila, J., Toulemon, D., Garnier, T., Garnier, A., Senger, B., Voegel, J. - C., et al. (2013). Bioaffinity Sensor Based on Nanoarchitectonic Films: Control of the Specific Adsorption of Proteins through the Dual Role of an Ethylene Oxide Spacer. Langmuir, 29(24), 7488–7498.
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Lefort, M., Jierry, L., Boulmedais, F., Benmlih, K., Lavalle, P., Senger, B., et al. (2013). Nanosized Films Based on Multicharged Small Molecules and Oppositely Charged Polyelectrolytes Obtained by Simultaneous Spray Coating of Interacting Species. Langmuir, 29(47), 14536–14544.
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Reisch, A., Tirado, P., Roger, E., Boulmedais, F., Collin, D., Voegel, J. - C., et al. (2013). Compact Saloplastic Poly(Acrylic Acid)/Poly(Allylamine) Complexes: Kinetic Control Over Composition, Microstructure, and Mechanical Properties. Advanced Functional Materials, 23(6), 673–682.
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Rydzek, G., Garnier, T., Schaaf, P., Voegel, J. - C., Senger, B., Frisch, B., et al. (2013). Self-Construction of Supramolecular Polyrotaxane Films by an Electrotriggered Morphogen-Driven Process. Langmuir, 29(34), 10776–10784.
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Tirado, P., Reisch, A., Roger, E., Boulmedais, F., Jierry, L., Lavalle, P., et al. (2013). Catalytic Saloplastics: Alkaline Phosphatase Immobilized and Stabilized in Compacted Polyelectrolyte Complexes. Advanced Functional Materials, 23(38), 4785–4792.
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2012

Chassepot, A., Gao, L., Nguyen, I., Dochter, A., Fioretti, F., Menu, P., et al. (2012). Chemically Detachable Polyelectrolyte Multilayer Platform for Cell Sheet Engineering. Chemistry of Materials, 24(5), 930–937.
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Chaubaroux, C., Vrana, E., Debry, C., Schaaf, P., Senger, B., Voegel, J. C., et al. (2012). Collagen-Based Fibrillar Multilayer Films Cross-Linked by a Natural Agent. Biomacromolecules, 13(7), 2128–2135.
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Davila, J., Chassepot, A., Longo, J., Boulmedais, F., Reisch, A., Frisch, B., et al. (2012). Cyto-mechanoresponsive Polyelectrolyte Multilayer Films. Journal of the American Chemical Society, 134(1), 83–86.
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Rydzek, G., Parat, A., Polavarapu, P., Baehr, C., Voegel, J. - C., Hemmerle, J., et al. (2012). One-pot morphogen driven self-constructing films based on non-covalent host-guest interactions. Soft Matter, 8(2), 446–453.
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Rydzek, G., Polavarapu, P., Rios, C., Tisserant, J. - N., Voegel, J. - C., Senger, B., et al. (2012). Morphogen-driven self-construction of covalent films built from polyelectrolytes and homobifunctional spacers: buildup and pH response. Soft Matter, 8(40), 10336–10343.
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Rydzek, G., Schaaf, P., Voegel, J. - C., Jierry, L., & Boulmedais, F. (2012). Strategies for covalently reticulated polymer multilayers. Soft Matter, 8(38), 9738–9755.
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Schaaf, P., Voegel, J. - C., Jierry, L., & Boulmedais, F. (2012). Spray-Assisted Polyelectrolyte Multilayer Buildup: from Step-by-Step to Single-Step Polyelectrolyte Film Constructions. Advanced Materials, 24(8), 1001–1016.
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2011

Gensel, J., Betthausen, E., Hasenoehrl, C., Trenkenschuh, K., Hund, M., Boulmedais, F., et al. (2011). Surface immobilized block copolymer micelles with switchable accessibility of hydrophobic pockets. Soft Matter, 7(23), 11144–11153.
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Kerdjoudj, H., Boulmedais, F., Berthelemy, N., Mjahed, H., Louis, H., Schaaf, P., et al. (2011). Cellularized alginate sheets for blood vessel reconstruction. Soft Matter, 7(7), 3621–3626.
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Lefort, M., Boulmedais, F., Jierry, L., Gonthier, E., Voegel, J. C., Hemmerle, J., et al. (2011). Simultaneous Spray Coating of Interacting Species: General Rules Governing the Poly(styrene sulfonate)/Poly(allylamine) System. Langmuir, 27(8), 4653–4660.
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Mjahed, H., Cado, G., Boulmedais, F., Senger, B., Schaaf, P., Ball, V., et al. (2011). Restructuring of exponentially growing polyelectrolyte multilayer films induced by salt concentration variations after film deposition. Journal of Materials Chemistry, 21(23), 8416–8421.
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Rydzek, G., Jierry, L., Parat, A., Thomann, J. - S., Voegel, J. - C., Senger, B., et al. (2011). Electrochemically Triggered Assembly of Films: A One-Pot Morphogen-Driven Buildup. Angewandte Chemie-International Edition, 50(19), 4374–4377.
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Trenkenschuh, K., Erath, J., Kuznetsov, V., Gensel, J., Boulmedais, F., Schaaf, P., et al. (2011). Tuning of the Elastic Modulus of Polyelectrolyte Multilayer Films built up from Polyanions Mixture. Macromolecules, 44(22), 8954–8961.
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2010

Dubacheva, G. V., Dumy, P., Auzely, R., Schaaf, P., Boulmedais, F., Jierry, L., et al. (2010). Unlimited growth of host-guest multilayer films based on functionalized neutral polymers. Soft Matter, 6(16), 3747–3750.
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El Haitami, A. E., Thomann, J. S., Jierry, L., Parat, A., Voegel, J. C., Schaaf, P., et al. (2010). Covalent Layer-by-Layer Assemblies of Polyelectrolytes and Homobifunctional Spacers. Langmuir, 26(14), 12351–12357.
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Guillaume-Gentil, O., Graf, N., Boulmedais, F., Schaaf, P., Voros, J., & Zambelli, T. (2010). Global and local view on the electrochemically induced degradation of polyelectrolyte multilayers: from dissolution to delamination. Soft Matter, 6(17), 4246–4254.
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Jierry, L., Ben Ameur, N., Thomann, J. S., Frisch, B., Gonthier, E., Voegel, J. C., et al. (2010). Influence of Cu(I)-Alkyne pi-Complex Charge on the Step-by-Step Film Buildup through Sharpless Click Reaction. Macromolecules, 43(8), 3994–3997.
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Kerdjoudj, H., Berthelemy, N., Boulmedais, F., Stoltz, J. F., Menu, P., & Voegel, J. C. (2010). Multilayered polyelectrolyte films: a tool for arteries and vessel repair. Soft Matter, 6(16), 3722–3734.
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Lefort, M., Popa, G., Seyrek, E., Szamocki, R., Felix, O., Hemmerlé, J., et al. (2010). Spray-On Organic/Inorganic Films: A General Method for the Formation of Functional Nano- to Microscale Coatings. Angew. Chem. Int. Ed., 49(52), 10110–10113.
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Mjahed, H., Voegel, J. C., Chassepot, A., Senger, B., Schaaf, P., Boulmedais, F., et al. (2010). Turbidity diagrams of polyanion/polycation complexes in solution as a potential tool to predict the occurrence of polyelectrolyte multilayer deposition. J. Colloid Interface Sci., 346(1), 163–171.
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Popa, G., Boulmedais, F., Zhao, P., Hemmerle, J., Vidal, L., Mathieu, E., et al. (2010). Nanoscale Precipitation Coating: The Deposition of Inorganic Films through Step-by-Step Spray-Assembly. ACS Nano, 4(8), 4792–4798.
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Rydzek, G., Thomann, J. S., Ben Ameur, N., Jierry, L., Mesini, P., Ponche, A., et al. (2010). Polymer Multilayer Films Obtained by Electrochemically Catalyzed Click Chemistry. Langmuir, 26(4), 2816–2824.
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Zahn, R., Boulmedais, F., Voros, J., Schaaf, P., & Zambelli, T. (2010). Ion and Solvent Exchange Processes in PGA/PAH Polyelectrolyte Multilayers Containing Ferrocyanide. J. Phys. Chem. B, 114(11), 3759–3768.
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2009

Dif, A., Boulmedais, F., Pinot, M., Roullier, V., Baudy-Floc'h, M., Coquelle, F. M., et al. (2009). Small and Stable Peptidic PEGylated Quantum Dots to Target Polyhistidine-Tagged Proteins with Controlled Stoichiometry. Journal Of The American Chemical Society, 131(41), 14738–14746.
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El Haitami, A. E., Martel, D., Ball, V., Nguyen, H. C., Gonthier, E., Labbe, P., et al. (2009). Effect of the Supporting Electrolyte Anion on the Thickness of PSS/PAH Multilayer Films and on Their Permeability to an Electroactive Probe. Langmuir, 25(4), 2282–2289.
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Laugel, N., Boulmedais, F., El Haitami, A. E., Rabu, P., Rogez, G., Voegel, J. C., et al. (2009). Tunable Synthesis of Prussian Blue in Exponentially Growing Polyelectrolyte Multilayer Films. Langmuir, 25(24), 14030–14036.
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Mjahed, H., Voegel, J. C., Senger, B., Chassepot, A., Rameau, A., Ball, V., et al. (2009). Hole formation induced by ionic strength increase in exponentially growing multilayer films. Soft Matter, 5(11), 2269–2276.
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2008

Grieshaber, D., Voros, J., Zambelli, T., Ball, V., Schaaf, P., Voegel, J. C., et al. (2008). Swelling and Contraction of Ferrocyanide-Containing Polyelectrolyte Multilayers upon Application of an Electric Potential. Langmuir, 24(23), 13668–13676.
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Malcher, M., Volodkin, D., Heurtault, B., Andre, P., Schaaf, P., Mohwald, H., et al. (2008). Embedded silver ions-containing liposomes in polyelectrolyte multilayers: Cargos films for antibacterial agents. Langmuir, 24(18), 10209–10215.
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Mjahed, H., Porcel, C., Senger, B., Chassepot, A., Netter, P., Gillet, P., et al. (2008). Micro-stratified architectures based on successive stacking of alginate gel layers and poly(L-lysine)-hyaluronic acid multilayer films aimed at tissue engineering. Soft Matter, 4(7), 1422–1429.
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Roullier, V., Grasset, F., Boulmedais, F., Artzner, F., Cador, O., & Marchi-Artzner, V. (2008). Small Bioactivated Magnetic Quantum Dot Micelles. Chemistry Of Materials, 20(21), 6657–6665.
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2007

Arntz, Y., Ball, V., Benkirane-Jessel, N., Boulmedais, F., Debry, C., Dimitrova, M., et al. (2007). Polymers in biomaterials science: from surface functionalisation to tissue engineering. Actualite Chimique, , 20–+.
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Mertz, D., Hemmerle, J., Boulmedais, F., Voegel, J. C., Lavalle, P., & Schaaf, P. (2007). Polyelectrolyte multilayer films under mechanical stretch. Soft Matter, 3, 1413–1420.
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2006

Ball, V., Michel, M., Boulmedais, F., Hemmerle, J., Haikel, Y., Schaaf, P., et al. (2006). Nucleation kinetics of calcium phosphates on polyelectrolyte multilayers displaying internal secondary structure. Crystal Growth & Design, 6(1), 327–334.
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Tezcaner, A., Hicks, D., Boulmedais, F., Sahel, J., Schaaf, P., Voegel, J. C., et al. (2006). Polyelectrolyte multilayer films as substrates for photoreceptor cells. Biomacromolecules, 7(1), 86–94.
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2005

Lavalle, P., Boulmedais, F., Ball, V., Mutterer, J., Schaaf, P., & Voegel, J. C. (2005). Free standing membranes made of biocompatible polyelectrolytes using the layer by layer method. Journal Of Membrane Science, 253(1-2), 49–56.
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Vodouhe, C., Schmittbuhl, M., Boulmedais, F., Bagnard, D., Vautier, D., Schaaf, P., et al. (2005). Effect of functionalization of multilayered polyelectrolyte films on motoneuron growth. Biomaterials, 26(5), 545–554.
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2004

Boulmedais, F., Frisch, B., Etienne, O., Lavalle, P., Picart, C., Ogier, J., et al. (2004). Polyelectrolyte multilayer films with pegylated polypeptides as a new type of anti-microbial protection for biomaterials. Biomaterials, 25(11), 2003–2011.
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Richert, L., Boulmedais, F., Lavalle, P., Mutterer, J., Ferreux, E., Decher, G., et al. (2004). Improvement of stability and cell adhesion properties of polyelectrolyte multilayer films by chemical cross-linking. Biomacromolecules, 5(2), 284–294.
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2003

Ball, V., Debreczeny, M., Boulmedais, F., Szalontai, B., Voegel, J. C., & Schaaf, P. (2003). Polyelectrolyte multilayers constructed from mixed polyelectrolyte solutions. In Abstracts Of Papers Of The American Chemical Society (Vol. 226, 56-PMSE).
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Boulmedais, F., Ball, V., Schwinte, P., Frisch, B., Schaaf, P., & Voegel, J. C. (2003). Buildup of exponentially growing multilayer polypeptide films with internal secondary structure. Langmuir, 19(2), 440–445.
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Boulmedais, F., Bozonnet, M., Schwinte, P., Voegel, J. C., & Schaaf, P. (2003). Multilayered polypeptide films: Secondary structures and effect of various stresses. Langmuir, 19(23), 9873–9882.
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Debreczeny, M., Ball, V., Boulmedais, F., Szalontai, B., Voegel, J. C., & Schaaf, P. (2003). Multilayers built from two component polyanions and single component polycation solutions: A way to engineer films with desired secondary structure. Journal Of Physical Chemistry B, 107(46), 12734–12739.
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2002

Boulmedais, F., Schwinte, P., Gergely, C., Voegel, J. C., & Schaaf, P. (2002). Secondary structure of polypeptide multilayer films: An example of locally ordered polyelectrolyte multilayers. Langmuir, 18(11), 4523–4525.
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