Delphine Chan-Seng received a B.Sc. degree in chemistry (2000) and a M.Sc. degree in Polymer Sciences (2002) from the University of Bordeaux (France). During her MSc, she spent 5 months working in the Macromolecular Chemistry II laboratory (University of Bayreuth, Germany) on the synthesis of hyperbranched polymers grafted on silica nanoparticles under the supervision of Axel H. E. MĂĽller and Hideharu Mori, and 7 months at the Laboratoire de Chimie des PolymĂ¨res Organiques (University of Bordeaux, France) under the supervision of Henri Cramail and Eric Cloutet on the synthesis of polyurethane particles in dispersed medium. She earned her Ph.D. degree in Polymer Chemistry (2007) from the University of Toronto (Canada) working under the direction of Michael K. Georges, where her thesis work dealt with controlled radical polymerization focusing on atom transfer radical polymerization under seeded emulsion conditions and the investigation of acrylates polymerization under nitroxide-mediated polymerization conditions. She then conducted postdoctoral research in the group of Todd Emrick at the University of Massachusetts at Amherst, where she focused on the synthesis of polymers for targeted applications, such as the synthesis of aliphatic polyesters and their post-polymerization functionalization used as coatings for drug-elution cardiovascular stents, and the synthesis of peptide-based comb polymers used as non-viral vectors for gene therapy. In 2011, she joined the Institut Charles Sadron as a CNRS researcher.
RESEARCH INTEREST KEYWORDS
Polymer synthesis, macromolecular engineering, post-polymerization modification, solid-phase synthesis, polymers for targeted applications
We are interested in developing polymers based on synthetic and natural building blocks combining organic chemistry, solid-phase peptide synthesis and polymer chemistry to further modulate the composition, topology and functionality of polymers and thus promote specific intrinsic properties to these polymers. Amino acid- and peptide-based polymers are aimed to find applications in biomedicine (e.g. delivery of small drugs, theranostics, gene therapy, cell adhesion, materials with antimicrobial activities), while the development of novel compatibilizers is targeted for composite materials and polymer blends.